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Pregaben CR 165mg Tablet 1 Strip
Pregabalin, the active ingredient, is a derivative of gamma-aminobutyric acid (GABA) and works by binding to the alpha2-delta site in voltage-gated calcium channels, which helps alleviate pain and control seizures.
Pregaben CR tablets are used for:
- Neuropathic pain associated with diabetic peripheral neuropathy
- Postherpetic neuralgia
- Adjunctive treatment for partial-onset seizures in patients 1 month and older
- Fibromyalgia
- Neuropathic pain linked to spinal cord injury
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✅ Description:
Pregaben CR 165 mg CR Tablet should be taken according to the dosage and duration prescribed by your doctor. It may cause drowsiness, so avoid driving or performing tasks requiring concentration until you are familiar with how it affects you. It can also lead to blurred vision or loss of vision, so if you experience any vision changes, inform your doctor immediately. If you notice any unusual changes in mood, behavior, new or worsening depression, or thoughts of suicide, consult your doctor. Do not stop taking the medication suddenly without consulting your doctor, as it may worsen your condition.
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✔️ Dosage
For diabetic peripheral neuropathy (DPN) in adults, the maximum recommended dose is 300 mg/day, starting with 150 mg/day and gradually increasing. For postherpetic neuralgia (PHN), the recommended dose is 150-300 mg/day, which can be increased up to 600 mg/day for those not achieving sufficient pain relief. For fibromyalgia, the dose is 300-450 mg/day, starting at 150 mg/day. For neuropathic pain due to spinal cord injury, the dose ranges from 150-600 mg/day.
Conversion from Pregabalin capsules to Pregabalin CR tablets: On the day of conversion, take the usual morning dose of Pregabalin capsules and start Pregabalin CR after dinner. If you miss a dose, follow the specific instructions regarding timing and meals to ensure the correct dose.
✔️ Administration:
Pregaben CR tablets should be taken orally, with or without food, after the evening meal. They should be swallowed whole and not crushed or chewed. If you miss a dose, follow the guidelines for when to take it based on your next meal time. When stopping the medication, it should be gradually tapered over a minimum of one week.
✔️ Interactions:
Pregaben CR is unlikely to have significant interactions with other drugs.
✔️ Side Effects
Common side effects include dizziness, sleepiness, dry mouth, swelling, blurred vision, weight gain, and difficulty concentrating. In children, increased weight and appetite may occur when used for seizures.
✔️ Pregnancy & Lactation
Pregabalin may pose risks to a fetus, and breastfeeding is not recommended during treatment due to potential risks.
✔️ Precautions:
- Discontinue immediately if severe allergic reactions (e.g., swelling of the throat, hives) occur.
- Use cautiously with CNS depressants, as it may cause respiratory depression.
- Gradual withdrawal over a week is necessary to avoid complications.
- Pregabalin can cause peripheral swelling and should be monitored if taken with certain antidiabetic medications.
✔️ Storage:
Store in a cool, dry place below 30°C, away from light and moisture, and keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
